Pragmatic Clinical Trials

Resources for Designing and Conducting Pragmatic Clinical Trials (PCTs)

View the Collaboratory handout

Visit the websites

NIH Collaboratory

• Lessons learned from 10 PCT Demonstration Projects
• Weekly Grand Rounds (public webinars) on topics in PCTs

Resources from Core Working Groups
• Electronic Health Records
• Phenotypes, Data Standards, and Data Quality
• Patient-Reported Outcomes
• Health Care Systems Interactions
• Regulatory/Ethics
• Biostatistics and Study Design
• Stakeholder Engagement

Rethinking Clinical Trials: A Living Textbook of Pragmatic Clinical Trials

A knowledge repository with documents and resources including:

• Topic Chapters on using electronic health records, patient-reported outcomes, and more
• Tools for Research from NIH Collaboratory and other groups
• Guidance documents
• White papers
• Toolkits
• Blog with news on PCTs (subscribe!)